Overview
What is Coalition To Cure Calpain 3?
Coalition To Cure Calpain 3 is a dedicated nonprofit organization, headquartered in Westport, Connecticut, focusing on Limb-Girdle Muscular Dystrophy Type 2A (LGMD2A/R1), a form of Calpainopathy. Their mission is twofold: to support research aimed at finding a cure or effective treatment for this condition, and to raise global awareness of the disease among medical professionals, patients, and the general public. The organization carries out this mission by funding various research projects, including drug screening, calcium handling improvement strategies, gene therapy vector optimization, and defining clinical endpoints. They also conduct concept elicitation/feasibility studies and unbiased systems-wide investigations, ensuring a comprehensive approach to understanding and combating the disease. With a small team of one dedicated individual, Coalition To Cure Calpain 3 demonstrates a strong commitment to making a significant impact on the lives of those affected by this muscular dystrophy.
Official website here: www.curecalpain3.org
Is Coalition To Cure Calpain 3 legitimate?
Coalition To Cure Calpain 3 is a legitimate nonprofit organization registered as a 501(c)(3) entity. Coalition To Cure Calpain 3 submitted a form 990, which is a tax form used by tax-exempt organizations in the U.S., indicating its operational transparency and adherence to regulatory requirements. Donations to this organization are tax deductible.
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Official website here: www.curecalpain3.org
What is the mission statement of Coalition To Cure Calpain 3?
The Coalition To Cure Calpain 3's mission is aimed at funding research to cure or treat Limb-Girdle Muscular Dystrophy Type 2A (LGMD2A/R1), a form of Calpainopathy. This organization also works towards raising global awareness about the disease among the scientific community, patients, and the public. Some of their research initiatives include drug screening in Capn3b-deficient zebrafish, improving calcium handling in LGMDR1/2A, optimizing and validating gene therapy vectors, defining clinical endpoints in LGMD, and conducting a concept elicitation/feasibility study for the Limb Girdle video assessment. These efforts are aimed at advancing understanding and potential treatments for the condition.
Official website here: www.curecalpain3.org
Who is the CEO of Coalition To Cure Calpain 3?
Michele Wrubel is the President of Coalition To Cure Calpain 3.
Official website here: www.curecalpain3.org
What is the revenue of Coalition To Cure Calpain 3?
Coalition To Cure Calpain 3's revenue in 2022 was $410,173.
Official website here: www.curecalpain3.org
Who are the executives of Coalition To Cure Calpain 3 and what are their salaries?
There is 1 employee at Coalition To Cure Calpain 3.
Here are 6 key members and their salaries:
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- Compensation: $10,000
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Official website here: www.curecalpain3.org
Where can I find the form 990 for Coalition To Cure Calpain 3?
Coalition To Cure Calpain 3's most recent form 990 was submitted in 2022 and can be accessed here.
Official website here: www.curecalpain3.org
Learn more at the official website: www.curecalpain3.org
Mission Statement of Coalition To Cure Calpain 3
The Coalition To Cure Calpain 3 is dedicated to achieving two primary objectives. Firstly, it aims to fund extensive research to discover potential cures or effective treatments for Limb-Girdle Muscular Dystrophy Type 2A (LGMD2A/R1), a form of Calpainopathy. This disease is a significant health concern that affects numerous individuals worldwide.
Secondly, the Coalition To Cure Calpain 3 is committed to raising global awareness about LGMD2A/R1 within the scientific community, among affected patients, and the general public. By fostering a broader understanding of this disease, the Coalition hopes to generate support and resources necessary for advancing research and ultimately finding a cure.
To accomplish its mission, the Coalition has supported various research projects led by renowned scientists and researchers. For instance, Pia Elustondo from Agada Biosciences is conducting drug screening in Calpain 3-deficient zebrafish. Similarly, Elisabeth Barton and Lan Wei-Lapierre from the University of Florida are working on strategies to improve calcium handling in LGMD2A/R1 patients. These are just a few examples of the collaborative efforts the Coalition is funding to combat this debilitating disease.
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Impact
October, 2024
The Coalition To Cure Calpain 3 has made significant strides in advancing research and awareness for Limb-Girdle Muscular Dystrophy Type 2A (LGMD2A), a form of calpainopathy. By funding vital research initiatives, it supports a diverse range of projects aimed at understanding and treating this debilitating condition.
Research funded includes innovative drug screening methods, such as the use of capn3b-deficient zebrafish by Agada Biosciences, which explores potential therapeutic options. Additionally, studies at esteemed institutions like the University of Florida and UCLA focus on improving calcium handling and optimizing gene therapy vectors, respectively, both critical aspects in the development of effective treatments.
The Coalition's efforts also extend to defining clinical endpoints for LGMD, as seen in the research led by Virginia Commonwealth University, allowing for more accurate assessments of treatment efficacy. By facilitating collaboration among leading scientists, such as those from Jackson Labs and the University of Calgary, the Coalition plays a pivotal role in advancing the understanding of calpain 3 and its implications in LGMD2A.
Moreover, the Coalition actively works to increase global awareness about this rare disease, ensuring that patients, the scientific community, and the public are informed and engaged. This multifaceted approach not only fosters research but also promotes a supportive environment for individuals affected by LGMD2A, ultimately aiming for a cure or effective treatment options.
This information is meant to be a general summary of Coalition To Cure Calpain 3. Please take the time to review official sources before making any decisions based upon the content provided here.
Financials
This financial information is from Propublica.
Other financial information:
This information is from the most recently submitted tax form from this organization, which was in 2022.
- Gross Receipts: $410,173
Assets and Liabilities:
- Total Assets: $151,536
- Total Liabilities: $261,298
- Net Assets: -$109,762
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Organization Details
Founding Year
2011
Phone
(203) 829-9656Principal Officer
Michele Wrubel
Main Address
15 COMPO PARKWAY, WESTPORT, CT, 06880
Website
www.curecalpain3.orgNTEE Category
Code: G125 - Disease
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