Arc Research Institute

Learn about this cause: What are the reviews? Is it Legit? Do I like the mission? What is the CEO's salary?

EIN: 871920284 ✦ Palo alto, CA ✦ Designated as a 501(c)(3)

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Overview

What is Arc Research Institute?

Arc Research Institute, headquartered in Palo Alto, California, is a nonprofit organization that partners with Stanford University, UCSF, and UC Berkeley to enable ambitious, long-term research agendas. Unlike traditional funding methods requiring grant applications, Arc offers scientists no-strings-attached, multi-year funding to invest in the development of experimental and computational technological tools. With a focus on complex diseases including cancer, neurodegeneration, and immune dysfunction, Arc's researchers collaborate across disciplines to make significant strides in scientific progress. The institute houses various labs, such as the Gilbert lab in synthetic biology, Hsu Lab at the intersection of synthetic biology and genomics, Konermann lab focusing on functional genomics, and Li Lab combining chemistry, biochemistry, immunology, and physiology. The organization's mission is to accelerate scientific discoveries, understand the root causes of diseases, and bridge the gap between research findings and their impact on patient care. With a team of 51 employees, Arc Research Institute is dedicated to advancing science and improving human health.


Official website here: www.arcinstitute.org/

What are the reviews and ratings of this charity?

The Arc Research Institute is not currently rated by Charity Navigator, primarily due to the lack of available data required for comprehensive assessment. This absence of a rating should not be perceived as inherently negative or positive, as the institute has only one year of electronically-filed IRS Form 990 data. Thus, it cannot be evaluated on parameters such as Accountability & Finance, Leadership & Adaptability, Culture & Community, and Impact & Measurement.

While historic ratings were largely based on Accountability and Finance, comprehensive evaluation is currently unattainable. The organization would need to consistently e-file additional fiscal years to achieve full transparency. The information provided does include salary data of several key staff members, which indicates transparency in employee compensation.

Although identified as a hospital or medical research organization, the Arc Research Institute remains an independent entity. However, the lack of user reviews on platforms like GreatNonprofits means there is limited public input on their on-the-ground effectiveness or community engagement. Therefore, a holistic appraisal of their impact and operation is currently challenging without further documented engagement or fiscal data.


This AI summary has been generated from information found on Charity Navigator.

Is Arc Research Institute legitimate?

Arc Research Institute is a legitimate nonprofit organization registered as a 501(c)(3) entity. Arc Research Institute submitted a form 990, which is a tax form used by tax-exempt organizations in the U.S., indicating its operational transparency and adherence to regulatory requirements. Donations to this organization are tax deductible.


Heare are some key statistics you may want to consider:

Executive Compensation: $1,405,920
Professional Fundraising Fees: $0
Other Salaries and Wages: $3,792,462

For more financial information, click here


Official website here: www.arcinstitute.org/

What is the mission statement of Arc Research Institute?

The Arc Research Institute is dedicated to advancing scientific progress and uncovering the root causes of complex diseases. Researchers at the institute, spanning various disciplines, work together to develop new technologies and innovative therapeutic concepts. By providing scientists with no-strings-attached funding, they can focus on rapid experimentation and collaboration. The organization's research areas include cancer, neurodegeneration, and immune dysfunction. Scientists at Arc are building CRISPR epigenetic editing tools, working on functional genomics approaches, and developing next-generation functional genomics to understand and target neurodegenerative disorders and innate immune pathways. The ultimate goal is to create more precise drugs that can prevent or treat specific diseases.


Official website here: www.arcinstitute.org/

Who is the CEO of Arc Research Institute?

Unavailable


Official website here: www.arcinstitute.org/

What is the revenue of Arc Research Institute?

Arc Research Institute's revenue in 2022 was $96,576,028.


Official website here: www.arcinstitute.org/

Who are the executives of Arc Research Institute and what are their salaries?

The average compensation at Arc Research Institute during 2022 was $101,929. There are 51 employees and 3 volunteers at Arc Research Institute.


Here are 16 key members and their salaries:


Nathaniel Friedman (Secretary/Director)
  • Compensation: $36,000
  • Related: $0
  • Other: $0
Alden J Woodrow (Coo)
  • Compensation: $76,944
  • Related: $0
  • Other: $5,017
Andrea Tiller (Treasurer (Until February 2022))
  • Compensation: $0
  • Related: $0
  • Other: $0
Julia M Kazaks (General Counsel)
  • Compensation: $128,793
  • Related: $0
  • Other: $10,886
Kaitlin E Browman (Coo (Until February 2022))
  • Compensation: $176,508
  • Related: $0
  • Other: $6,691
Lynn M Hendrickson (University Relations & Academic Affairs)
  • Compensation: $187,122
  • Related: $0
  • Other: $7,448
Mike Barsotti (Treasurer (Until February 2022))
  • Compensation: $0
  • Related: $0
  • Other: $0
Nicolle D Seuss (Senior Operations Program Manager)
  • Compensation: $220,150
  • Related: $0
  • Other: $16,484
Patrick D Hsu Phd (Core Investigator)
  • Compensation: $272,435
  • Related: $0
  • Other: $3,819
Rose E Harris (Finance)
  • Compensation: $120,092
  • Related: $0
  • Other: $0
Silvana M Konermann Phd (Executive Director)
  • Compensation: $137,053
  • Related: $0
  • Other: $945
April Pawluk (Senior Scientist)
  • Compensation: $144,000
  • Related: $0
  • Other: $0
Jennifer A Moss (Senior Recruiter)
  • Compensation: $273,065
  • Related: $0
  • Other: $11,458
Lingyin Li (Core Investigator)
  • Compensation: $142,869
  • Related: $0
  • Other: $1,472
Matthew G Durrant Phd (Senior Scientist)
  • Compensation: $192,210
  • Related: $0
  • Other: $20,486
Rose-Marie Lyght (Senior Finance Manager)
  • Compensation: $157,538
  • Related: $0
  • Other: $20,536


Official website here: www.arcinstitute.org/

Where can I find the form 990 for Arc Research Institute?

Arc Research Institute's most recent form 990 was submitted in 2022 and can be accessed here.


Official website here: www.arcinstitute.org/

Learn more at the official website: www.arcinstitute.org/

Mission Statement of Arc Research Institute

Arc Research Institute, a renowned nonprofit organization, is dedicated to propelling scientific advancements and unraveling the underlying causes of intricate diseases. With a team of researchers spanning various disciplines, the institute concentrates on investigating fundamental biological mechanisms, innovating new technologies, and exploring novel therapeutic concepts. By doing so, they strive to bridge the gap between groundbreaking discoveries and their impact on patient care.

Based in California, Arc Research Institute partners with esteemed academic institutions, including Stanford University, UCSF, and UC Berkeley. The organization's unique approach grants scientists the freedom to focus on the rapid development of experimental and computational tools without the need for external grants. This enables ambitious, long-term research agendas, which is crucial for tackling complex diseases such as cancer, neurodegeneration, and immune dysfunction.

The Gilbert lab, a part of Arc Research Institute, specializes in synthetic biology, functional genomics, and cancer biology. They leverage CRISPR epigenetic editing tools to manipulate genes and regulatory elements, aiming to shed light on the intricacies of deadly human cancers like metastasis and drug resistance. On the other hand, the Hsu Lab explores the intersection of synthetic biology and genomics to invent novel biotechnologies that enhance human health. The Konermann lab is committed to understanding the neuronal system and neurodegenerative diseases using next-generation functional genomics, with the ultimate goal of creating rationally targeted therapeutics.

Moreover, the Li Lab, another research division within Arc, combines chemistry, biochemistry, immunology, and physiology to unlock the mysteries of innate immunity. These pathways, serving as the first line of defense against pathogens, present numerous opportunities for scientists to explore novel chemistry and develop targeted drugs to prevent or treat specific diseases. However, most current modulators of innate immunity are nonspecific and poorly understood, limiting their therapeutic potential. The Li lab aims to enhance our comprehension of these pathways and facilitate the development of more precise drugs for various applications.

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Impact




October, 2024

Arc Research Institute significantly impacts scientific progress by accelerating the understanding of complex diseases through innovative research initiatives. By fostering collaboration among researchers across diverse disciplines, Arc enables the exploration of fundamental biological mechanisms and the development of groundbreaking technologies. This multidisciplinary approach is crucial for tackling pressing medical challenges such as cancer, neurodegeneration, and immune dysfunction.

Headquartered in Palo Alto, California, Arc operates in partnership with esteemed institutions like Stanford University, UCSF, and UC Berkeley. Providing scientists with no-strings-attached, multi-year funding allows them to focus on ambitious, long-term research agendas without the constraints of conventional grant applications. This flexibility is vital for nurturing groundbreaking ideas and rapidly developing experimental tools.

The various labs at Arc exemplify this impact. The Gilbert lab is spearheading advancements in CRISPR technology to combat deadly cancers, targeting issues like metastasis and drug resistance. Meanwhile, the Hsu Lab innovates at the convergence of synthetic biology and genomics, inventing new biotechnologies aimed at enhancing human health. The Konermann lab applies next-generation functional genomics to elucidate the pathways involved in neurodegenerative diseases, aiming for targeted therapeutics. Lastly, the Li Lab focuses on innate immunity, striving to uncover precise therapeutic avenues to combat various diseases, from autoimmune disorders to cancers.

Through these multidisciplinary efforts, Arc Research Institute not only advances scientific knowledge but also strives to close the gap between discoveries and their application in patient care, ultimately enhancing human health and wellbeing.




This information is meant to be a general summary of Arc Research Institute. Please take the time to review official sources before making any decisions based upon the content provided here.


Financials

This financial information is from Propublica.

Revenue
$96,576,028 (2022)
Expenses
$32,795,122 (2022)
Efficiency

Other financial information:

This information is from the most recently submitted tax form from this organization, which was in 2022.

  • Investment Income: -$784,012
  • Gross Receipts: $103,837,078

Assets and Liabilities:

  • Total Assets: $150,115,619
  • Total Liabilities: $77,639,349
  • Net Assets: $72,476,270

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Organization Details

Founding Year

2021

Main Address

3181 Porter Dr, Palo Alto, CA, 943041249

NTEE Category

Code: H99 - Medical research

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