Overview
What is Als Cure Project Inc?
Als Cure Project Inc, based in Pleasanton, California, is a nonprofit organization dedicated to combating Amyotrophic Lateral Sclerosis (ALS). Their primary mission involves leading scientific research, specifically focusing on identifying ALS bio-markers and understanding the disease mechanism. This year, they have funded studies at Stanford University and Sheffield University, utilizing advanced supercomputing technology to model TDP-43 protein aggregates, which are prevalent in over 95% of ALS cases. Their research aims to ultimately provide insights into the disease mechanism and potentially lead to new treatment options for ALS.
Official website here: www.alscure.net
What are the reviews and ratings of this charity?
Charity Navigator Rating: 86% (Three-Star out of Four Star Rating)
Als Cure Project Inc has achieved a commendable score of 86%, reflecting its strong performance in accountability and finance. The rating is driven entirely by its accountability measures, which are vital indicators of a nonprofit's operational integrity. With 100% of its board members being independent, the organization demonstrates a commitment to unbiased governance.
Strengths noted in the evaluation include no material diversion of assets and a high program expense ratio of 97.38%, indicating that most of its resources are directed towards its mission. Additionally, the organization's tax form is readily available on its website, enhancing transparency. The presence of various policies, like the conflict of interest policy, further underscores its dedication to maintaining ethical standards.
However, there are areas for improvement, particularly the absence of a whistleblower policy and a document retention and destruction policy, which both scored zero out of seven points. Addressing these gaps could strengthen the organization’s accountability framework and overall trust with stakeholders.
This AI summary has been generated from information found on Charity Navigator.
Is Als Cure Project Inc legitimate?
Als Cure Project Inc is a legitimate nonprofit organization registered as a 501(c)(3) entity. Als Cure Project Inc submitted a form 990, which is a tax form used by tax-exempt organizations in the U.S., indicating its operational transparency and adherence to regulatory requirements. Donations to this organization are tax deductible.
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Official website here: www.alscure.net
What is the mission statement of Als Cure Project Inc?
The Als Cure Project Inc's primary objective is to spearhead scientific research aimed at identifying bio-markers and understanding the disease mechanism of Amyotrophic Lateral Sclerosis (ALS). This year, the organization has funded research initiatives at Stanford University and Sheffield University, utilizing advanced technologies such as multi-gene modeling and the Lawrence Livermore National Lab's supercomputer, Sierram, for multi-modal and physics-based modeling of TDP-43 protein aggregates, which are present in over 95% of ALS cases. The goal is to gain a deeper understanding of the ALS disease process, specifically focusing on the formation of aberrant TAR DNA-binding protein 43 (TDP-43) inclusions or clusters that transform into pathological, amyloid-like fibrils.
Official website here: www.alscure.net
What is the revenue of Als Cure Project Inc?
Als Cure Project Inc's revenue in 2023 was $164,489.
Official website here: www.alscure.net
Who are the executives of Als Cure Project Inc and what are their salaries?
There 20 volunteers at Als Cure Project Inc.
Here are 8 key members and their salaries:
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Official website here: www.alscure.net
Where can I find the form 990 for Als Cure Project Inc?
Als Cure Project Inc's most recent form 990 was submitted in 2023 and can be accessed here.
Official website here: www.alscure.net
Learn more at the official website: www.alscure.net
Mission Statement of Als Cure Project Inc
Als Cure Project Inc, a dedicated organization, is committed to spearheading scientific research aimed at identifying bio-markers and understanding the disease mechanism associated with Amyotrophic Lateral Sclerosis (ALS). This year, the organization has funded projects at both Stanford University and Sheffield University, focusing on multi-gene modeling. Furthermore, Als Cure Project Inc is supporting research that utilizes the Lawrence Livermore National Lab's supercomputer, Sierram, to conduct multi-modal longitudinal modeling and physics-based modeling of TDP-43 protein aggregates. These aggregates are present in over 95% of ALS cases, and the project aims to shed light on their formation, evolution, and impact on the disease.
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Impact
October, 2024
Als Cure Project Inc significantly impacts the understanding and treatment of Amyotrophic Lateral Sclerosis (ALS) through cutting-edge scientific research. By leading initiatives aimed at identifying biomarkers and elucidating the disease mechanisms of ALS, the organization has become a key player in the fight against this devastating condition.
One of the organization's notable achievements is its funding of a physics-based modeling project at Lawrence Livermore National Laboratory, which utilizes one of the world’s fastest supercomputers. This project focuses on the formation and transition of aberrant TDP-43 protein inclusions into pathological amyloid-like fibrils—crucial processes in over 95% of ALS cases. Such insights are vital for developing targeted therapies and improving diagnostic tools.
Additionally, the ALS Cure Project has supported multi-gene modeling research at prestigious institutions such as Stanford University and Sheffield University. These efforts encompass multi-modal longitudinal studies and advanced modeling techniques that further our understanding of TDP-43 aggregates and their role in ALS.
Overall, the ALS Cure Project Inc's commitment to pioneering research not only propels scientific discovery but also aims to translate findings into tangible benefits for those affected by ALS, ultimately driving progress toward effective treatments and a potential cure.
This information is meant to be a general summary of Als Cure Project Inc. Please take the time to review official sources before making any decisions based upon the content provided here.
Financials
This financial information is from Propublica.
Other financial information:
This information is from the most recently submitted tax form from this organization, which was in 2023.
- Gross Receipts: $341,443
Assets and Liabilities:
- Total Assets: $178,157
- Total Liabilities: $0
- Net Assets: $178,157
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Organization Details
Founding Year
2019
Principal Officer
Mike Piscotty
Website
www.alscure.netNTEE Category
Code: H50 - Medical research
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